Female unexplained infertility: A disease with imbalanced adaptive immunity

Unexplained Infertility

Dexamethasone in unexplained infertility.

OBJECTIVE To determine if dexamethasone could be a suitable option in the treatment of patients with unexplained infertility. METHODS This study was carried out in the Obstetrics Department of Amir University Hospital, Semnan, Iran, from April 2001 to May 2008. One hundred and twenty-four cases of unexplained infertility that underwent ovulation induction and intrauterine insemination (IUI) (...

Anticardiolipin antibodies in women with unexplained infertility.

Concept of autoimmune basis of infertility is still controversial, particularly regarding the presence of non-organ specific autoantibodies. Non-organ specific anticardiolipin (aCL) and antithyroglobulin (TgAt) antibodies were detected in infertile women. Both partners were evaluated according to the criteria of The American Society for Reproductive Medicine. All the results were normal in case...

Overtreatment in couples with unexplained infertility.

STUDY QUESTION What is the percentage of overtreatment, i.e. fertility treatment started too early, in couples with unexplained infertility who were eligible for tailored expectant management? SUMMARY ANSWER Overtreatment occurred in 36% of couples with unexplained infertility who were eligible for an expectant management of at least 6 months. WHAT IS KNOWN ALREADY Prognostic models in repr...

Pregnancy Outcome after Office Microhysteroscopy in Women with Unexplained Infertility

Background Hysteroscopy offers diagnostic accuracy and the ability to treat uterine pathology. The current study aimed to review the findings and feasibility of the proposed office-based diagnostic and operative microhysteroscopy in previously diagnosed women with unexplained infertility and to evaluate the post-microhysteroscopic pregnancy outcome in a-year follow-up period. MaterialsAndMethod...